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    • Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes 

      Na Zhao; Chia-Chen Liu; Alexandra J. Van Ingelgom; Yuka A. Martens; Cynthia Linares; Joshua A. Knight; Meghan M. Painter; Patrick M. Sullivan; Guojun Bu (Elsevier Inc, 2017-09)
      【Abstract】Diabetes and impaired brain insulin signaling are linked to the pathogenesis of Alzheimer's disease (AD). The association between diabetes and AD-associated amyloid pathology is stronger among carriers of the ...