Now showing items 546-565 of 2442

    • Isatis tinctoria L combined with co-stimulatory molecules blockade prolongs survival of cardiac allografts in alloantigen-primed mice 

      Kang, Xiangpeng; Chen, Jibing; Qin, Qing; Wang, Feng; Wang, Yongzhi; Lan, Tianshu; Xu, Shuo; Wang, Feiyu; Xia, Junjie; Ekberg, Henrik; Qi, Zhongquan; Liu, Zhongchen; 齐忠权; 刘忠臣 (TRANSPL IMMUNOL, 2010-05)
      Memory T cells present a unique challenge in transplantation. Although memory T cells express robust immune responses to invading pathogens. they may be resistant to the effects of immunosuppressive therapies used to prolong ...
    • Ischemic stroke as a primary symptom of neurosyphilis among HIV-negative emergency patients 

      Liu, Li-Li; Zheng, Wei-Hong; Tong, Man-Li; Liu, Gui-Li; Zhang, Hui-Lin; Fu, Zuo-Gen; Lin, Li-Rong; Yang, Tian-Ci; 杨天赐 (ELSEVIER SCIENCE BV, 2012-06-15)
      Background: Neurosyphilis is known as "the great imitator" or "the great impostor" because of its wide range of clinical symptoms. A high misdiagnosis rate of ischemic stroke was observed among neurosyphilis patients in ...
    • Islet transplantation reverses the effects of maternal diabetes on mouse oocytes 

      Cheng, Pan-Pan; Xia, Jun-Jie; Wang, Hai-Long; Chen, Ji-Bing; Wang, Fei-Yu; Zhang, Ye; Huang, Xin; Zhang, Quan-Jun; Qi, Zhong-Quan; 张业 (2011-04)
      Maternal diabetes adversely affects preimplantation embryo development and oocyte maturation. Thus, it is important to identify ways to eliminate the effects of maternal diabetes on preimplantation embryos and oocytes. The ...
    • iTRAQ Based Quantitative Proteomics Approach Validated the Role of Calcyclin Binding Protein (CacyBP) in Promoting Colorectal Cancer Metastasis 

      Ghosh, Dipanjana; Li, Zhihan; Tan, Xing Fei; Lim, Teck Kwang; Mao, Yubin; Lin, Qingsong; 毛宇彬 (AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2013)
      Keeping continuity with our previous study that revealed direct correlations between CRC metastasis and enhanced CacyBP protein levels, here we attempt to improve our understanding of the mechanisms involved within this ...
    • JH11Fab′片段的制备及其在人肝癌裸鼠模型的放射免疫显像 

      颜江华; 苏金华; 俞浩; 陈福 (1998)
      利用胃蛋白酶酶切单克隆抗体JH11,经SEPHAdEXg-150分离获得JH11fAb′,得率约15%.用氯胺T碘标法制备131I-JH11fAb′,观测其在荷人肝细胞癌bEl-7402裸鼠模型的定位显像作用,腹腔注射131I-JH11fAb′后24~120H,肿瘤部位放射性物质浓集,并清楚显像,其中尤以96H为佳.131I-JH11fAb′注射后96H,在13种器官的T/nT比值均大于3.0,肿瘤的定位指数为3.80.这表明JHfAb ...
    • JNK2 Participates in Spindle Assembly during Mouse Oocyte Meiotic Maturation 

      Huang, Xin; Tong, Jing-Shan; Wang, Zhen-Bo; Yang, Cai-Rong; Qi, Shu-Tao; Guo, Lei; Ouyang, Ying-Chun; Quan, Song; Sun, Qing-Yuan; Qi, Zhong-Quan; Huang, Ru-Xin; Wang, Hai-Long; 齐忠权; 王海龙 (MICROSC MICROANAL, 2011-04)
      It is well known that c-Jun N-terminal kinase (JNK) plays pivotal roles in various mitotic events, but its function in mammalian oocyte meiosis remains unknown. In this study, we found that no specific JNK2 signal was ...
    • Keyhole Endoscopic Hematoma Evacuation in Patients 

      Zhu, Hongwei; 朱宏伟; Wang, Zhanxiang; Shi, Wei (TURKISH NEUROSURGICAL SOC, 2012-05)
      AIM: Keyhole endoscopy is a promising therapeutic option for spontaneous intracerebral hemorrhage (ICH). We sought to compare the clinical outcomes between keyhole endoscopy surgery and craniotomy for basal ganglia ICH. ...
    • Ki-67与脑膜瘤分级及复发的相关性分析 

      王文阳; 卢珍玲; 林晓宁; 杨修 (2018-11-25)
      目的分析Ki-67与脑膜瘤分级及复发的相关性。方法收集2005年1月—2013年5月的172例脑外科脑膜瘤初次手术治疗患者病理标本,采用免疫组化染色检测标本中Ki-67的阳性率,随访患者5年内复发情况,并分析Ki-67与脑膜瘤分级及复发的相关性。结果Ⅰ、Ⅱ、Ⅲ级脑膜瘤患者的Ki-67阳性率分别为(1.70±1.13)%、(4.81±3.63)%和(25.00±8.53)%,Ki-67阳性率逐渐增高,差异有统计学意义(Z=79.474,P ...
    • Knockdown of Li-cadherin increases metastatic behaviors of LoVo cells 

      Yu, Qiong-Fang; Dong, Wei-Guo; Ren, Jian-Lin; 任建林 (J CANCER RES CLIN, 2010-09)
      The aim of this study was to investigate the role of Li-cadherin in invasion and metastasis in LoVo cells. We applied RNA interference mediated downregulation of Li-cadherin expression in LoVo cells. Li-cadherin expression ...
    • L-type calcium current in right ventricular outflow tract myocytes of rabbit heart 

      Liang ShengHui; Lin ChenHui; Li Yuan; Liu TaiFeng; Wang Yan; 王焱 (SCI CHINA LIFE SCI, 2012-01)
      The mechanism of idiopathic ventricular tachycardia originating from the right ventricular outflow tract (RVOT) is not clear. Many clinical reports have suggested a mechanism of triggered activity. However, there are few ...
    • Label-free DNA sensor by boron-doped diamond electrode using an ac impedimetric approach 

      Weng, J.; Zhang, J. F.; Li, H.; Sun, L. P.; Lin, C. H.; Zhang, Q. Q.; 张其清 (2008-09-15)
      An electrochemical biosensor using a boron-doped diamond (BDD) electrode is described for differentiating between gene sequences according to DNA hybridization events using an ac impedimetric approach. BDD electrodes were ...
    • Laboratorial characteristics of patients with diarrhoea suffering from egg white allergy 

      Liu, F.; Lin, L. -R.; Zhang, H. -L.; Liu, G. -L.; Tong, M. -L.; Zeng, Y. -L.; Huang, S. -J.; Huang, C. -L.; Liu, L. -L.; Yang, T. -C.; 刘风 (ELSEVIER DOYMA SL, 2014 MAY-J)
      Background: Egg allergy is associated with diarrhoea( symptoms. However, the mechanism underlying allergic diarrhoea remains unclear. Objective: To determine whether egg white-specific IgE antibodies coexist with egg ...
    • Laboratory findings in neurosyphilis patients with epileptic seizures alone as the initial presenting symptom 

      Tong, Man-Li; Liu, Li-Li; Zeng, Yan-Li; Zhang, Hui-Lin; Liu, Gui-Li; Zheng, Wei-Hong; Dong, Jie; Wu, Jing-Yi; Su, Yuan-Hui; Lin, Li-Rong; Yang, Tian-Ci; 刘莉莉; 郑维红; 林丽蓉; 杨天赐 (ELSEVIER SCIENCE INC, 2013)
      A retrospective chart review was performed to characterize the clinical presentation, the characteristic combination of serologic and cerebrospinal fluid (CSF) abnormalities, and the neuroimaging findings of neurosyphilis ...
    • Laparoscopic liver resection as a safe and efficacious alternative to open resection for colorectal liver metastasis: a meta-analysis 

      Zhou, Yanming; Xiao, Yaqing; Wu, Lupeng; Li, Bin; Li, Hua; 周彦明; 李滨 (BIOMED CENTRAL LTD, 2013-Oct 1)
      Background: The safety and efficacy of laparoscopic liver resection (LLR) for colorectal liver metastasis (CLM) remain to be established. A meta-analysis was undertaken to compare LLR and open liver resection (OLR) for CLM ...
    • Laparoscopic versus open distal pancreatectomy: A meta-analysis 

      Sui, Cheng-Jun; Li, Bin; Yang, Jia-Mei; Wang, Shuang-Jia; Zhou, Yan-Ming; 李滨; 周彦明 (ASIAN J SURG, 2012-01)
      Objective: Laparoscopic distal pancreatectomy (LDP) is a minimally invasive surgical technique. The aim of the present study was to evaluate the currently available literature and compare the short-term clinical outcomes ...
    • Layered zirconium phosphate-supported metalloporphyrin: Synthesis and catalytic application 

      Wang, H. Y.; Ji, W. D.; Han, D. X.; 韩大雄 (2008-09)
      This paper reports a new route for the preparation of layered alpha-zirconium phosphate (alpha-ZrP)-supported metalloporphyrin MnTMPyP. MnTMPyP was intercalated into alpha-ZrP using alpha-ZrP.BA (i.e. pre-intercalated ...
    • LC-MS/MS quantification of N-acetylneuraminic acid, N-glycolylneuraminic acid and ketodeoxynonulosonic acid levels in the urine and potential relationship with dietary sialic acid intake and disease in 3- to 5-year-old children 

      Chen, Yue; Pan, Lili; Liu, Ni; Troy, Frederic A.; Wang, Bing; 王冰 (CAMBRIDGE UNIV PRESS, 2014-01-28)
      Red meat and dairy products contain high sialic acid (Sia) levels, but the metabolic fate and health impact in children remain unknown. The aims of the present study were to quantify the levels of urinary Sia N-acetylneuraminic ...
    • LC-MS/MS法检测猪内脏和肌肉中N-乙酰神经氨酸、N-羟乙酰氨酸和脱氨神经氨酸浓度的研究 

      吉素娜; 王芳; 张盼望; 陈越; 杨长伟; 王冰 (2017)
      目的:建立液相色谱-三重四级杆质谱联用法(LC-MS/MS)测定猪内脏和肌肉组织中唾液酸N-乙酰神经氨酸(Neu5Ac)、N-羟乙酰神经氨酸(Neu5Gc)和脱氨神经氨酸(KDN)浓度的分析方法。方法:将内脏肉组织匀浆后,利用三氟乙酸(TFA)将结合态的唾液酸从糖脂或糖蛋白链上解离下来后进样分析。色谱条件:色谱柱为ZORBAX Eclipse Plus C18(5μm,4.6×250 mm,Waters),流动相为0.1%醋酸铵-100 ...
    • Lens Culinaris Agglutinin-Reactive Fraction of Alpha-Fetoprotein as a Marker of Prognosis and a Monitor of Recurrence of Hepatocellular Carcinoma After Curative Liver Resection 

      Zhang, Xiao-Feng; Lai, Eric C. H.; Kang, Xiao-Yan; Qian, Hai-Hua; Zhou, Yan-Ming; Shi, Le-Hua; Shen, Feng; Yang, Ye-Fa; Zhang, Yu; Lau, Wan Yee; Wu, Meng-Chao; Yin, Zheng-Feng; 周彦明 (ANN SURG ONCOL, 2011-08)
      The aim of this study was to determine the role of Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein (AFP-L3) as a prognostic marker and a monitor marker of recurrence after curative resection of hepatocellular ...
    • Lica光激化学发光免疫分析系统检测乙肝两对半的性能评价 

      张阳根; 胡桂华; 黄林江 (2011-11-30)
      目的对Lica光激化学发光免疫分析系统主要性能进行初步评价。方法以美国临床实验室标准化协会(CLSI)制定的评价标准,通过一系列实验设计,对Lica光激化学发光免疫分析系统进行乙肝"两对半"检测的精密度、准确度、线性、分析灵敏度等进行评价。结果 Lica光激化学发光免疫分析系统进行乙肝"两对半"检测,批内不精密度变异系数在1.49%~4.40%,总不精密度在2.15%~6.22%,回收试验的回收率为96.32%~106.54%,HbsA ...