Now showing items 474-493 of 2316

    • Identification of annexin A1 as a proinvasive and prognostic factor for lung adenocarcinoma 

      Liu, Ying-Fu; Zhang, Peng-Fei; Li, Mao-Yu; Li, Quo-Qing; Chen, Zhu-Chu; 刘迎福 (CLIN EXP METASTAS, 2011-06)
      Metastasis is the most common cause of death in lung cancer patients and is a major obstacle to the successful treatment. To discover novel metastasis-related proteins in lung adenorcinoma (AdC), quantitative proteomic ...
    • Identification of differential gene expressions in colorectal cancer and polyp by cDNA microarray 

      Dai, Yi-Chen; Zhu, Xiao-San; Nan, Qing-Zhen; Chen, Zhang-Xin; Xie, Jun-Pei; Fu, Yu-Ka; Lin, Yuan-Yuan; Lian, Qing-Na; Sang, Qiao-Fang; Zhan, Xiao-Juan; 林园园; 戴益琛 (WORLD J GASTROENTERO, 2012-02-14)
      AIM: To screen the differential expressed genes in colorectal cancer and polyp tissue samples. METHODS: Tissue specimens containing 16 cases of colorectal adenocarcinoma and colorectal polyp vs normal mucosae were collected ...
    • Identification of Motor and Sensory Fascicles in Peripheral Nerve Trunk Using Immunohistochemistry and Micro-Raman Spectroscopy 

      Wang, Hu; Ma, Feiyu; Wang, Feng; Liu, Dongxin; Li, Xuedong; Du, Shixin; 王凤 (J TRAUMA, 2011-09)
      Objective: To explore a time-efficient method of identifying motor and sensory fascicles in peripheral nerve trunk. Methods: Thirty Wistar rats were selected to obtain whole spine. The spinal dorsal roots and ventral roots, ...
    • Identification of two novel splicing variants of murine NTE-related esterase 

      Chang, Ping-An; Wang, Zhan-Xiang; 王占祥; Long, Ding-Xin; Qin, Wen-zhen; Wei, Chen-ying; Wu, Yi-Jun (ELSEVIER SCIENCE BV, 2012-04-15)
      NTE-related esterase (NRE) is an insulin-regulated lysophospholipase with homology to neuropathy target esterase (NTE), which plays a role in energy metabolism. Here, we reported two alternative splicing variants of the ...
    • IL-17 promotes Type 1 T cell response through modulating dendritic cell function in acute allograft rejection 

      Duan, Lihua; Chen, Jie; Xia, Quansong; Chen, Liying; Fan, Kai; Sigdel, K. R.; Fang, Min; Zheng, Fang; Shi, Guixiu; Gong, Feili; 陈杰; 石桂秀 (ELSEVIER SCIENCE BV, 2014 JUN)
      IL-17 is a cytokine that produced by various type of cell. Previous studies have been shown that IL-17 plays a critical role in the pathogenesis of different diseases. However, few studies have addressed the source and ...
    • IL-18BP重组蛋白对TNF-α诱导的人脐静脉内皮细胞的作用研究 

      李刚; 贺芙云; 常贺; 黄明山; 王焱 (2013-01-01)
      目的探讨人重组白细胞介素-18结合蛋白(rhIL-18BP)对肿瘤坏死因子(TNF-α)诱导的内皮细胞炎症、凋亡的影响。方法体外培养人脐静脉内皮细胞(HUVECs),用20 ng/ml的TNF-α和不同质量浓度的rhIL-18BP孵育相应时间,提取mRNA并用PCR及实时定量PCR检测细胞因子(IL-6、IL-8)、黏附分子(ICAM-1、VCAM-1)的mRNA表达;ELISA法检测细胞上清液中细胞因子(IL-6、IL-8)、可溶性黏 ...
    • IL-18、IL-12及相关因子在大鼠实验性自身免疫心肌炎心肌中的表达时程和特征 

      常贺; 李刚; 张乐; 邹军; 朱铉; 金鑫 (2010-06-01)
      目的:探讨IL-18、IL-12及相关细胞因子在大鼠实验性自身免疫心肌炎(EAM)心肌中的表达时程和特征。方法:以猪心脏肌球蛋白加等体积弗氏完全佐剂,辅结核杆菌H37Ra株之乳液为抗原,于Lewis大鼠双后肢皮下注射造模(EAM);用胶原酶灌流和网筛过滤法分离纯化心肌细胞;经免疫组化技术评估心肌损伤程度;按实时荧光定量法测急性期和慢性期,IL-18、IL-12及相关因子(IL-18R,IL-18RAcPL,IL-18BP以及IL-12p ...
    • IL-19及其相关因子在大鼠自身免疫性心肌炎各时程的表达特征 

      常贺; 吴梁安; 李刚; 吴韦因; 王焱 (2012-01-01)
      目的探讨IL-19及其相关因子在大鼠实验性自身免疫性心肌炎(EAM)急慢性期各时程的表达特征。方法建立大鼠EAM模型;病理学评估EAM急慢性期(normal、3w、3m、6m)心肌损伤程度;应用实时荧光定量RT-PCR检测IL-19及其两条受体链IL-20R1/IL-20R2,IL-20在EAM大鼠各脏器(心、肝、脾、肾)以及在心肌组织各时程(normal、3w、3m、6m)的mRNA表达;进一步应用ELISA法检测IL-19和IL-2 ...
    • IL-1R Ⅱ重组质粒导入对大鼠实验性自身免疫性心肌炎的治疗作用 

      王焱; 吴韦因; 吴梁安; 李刚; 苏茂龙; 常贺 (2012-03-15)
      目的:评估编码Ⅱ型白细胞介素-1受体(typeⅡinterleukin-1 receptor,IL-1RⅡ)的重组质粒在大鼠实验性自身免疫性心肌炎(experimental autoimmune myocarditis,EAM)中的治疗效果。方法:将猪心室肌球蛋白与等体积完全弗氏免疫佐剂充分混匀后,于第0 d Lewis大鼠双后足皮下注射制作EAM模型,第6 d应用流体动力学方法进行重组质粒IL-1RⅡ的体内导入,第17 ...
    • IL-1RⅡ重组质粒导入对大鼠实验性自身免疫性心肌炎的治疗作用 

      王焱; 吴韦因; 吴梁安; 李刚; 苏茂龙; 常贺 (2012)
      目的:评估编码Ⅱ型白细胞介素-1受体(TyPEⅡInTErlEukIn-1 rECEPTOr,Il-1rⅡ)的重组质粒在大鼠实验性自身免疫性心肌炎(EXPErIMEnTAl AuTOIMMunE MyOCArdITIS,EAM)中的治疗效果。方法:将猪心室肌球蛋白与等体积完全弗氏免疫佐剂充分混匀后,于第0 d lEWIS大鼠双后足皮下注射制作EAM模型,第6 d应用流体动力学方法进行重组质粒Il-1rⅡ的体内导入,第17 ...
    • Image-guided resection of malignant gliomas using FLuorescent nanoparticles 

      Su, Xinhui; Cheng, Kai; Wang, Charlie; Xing, Lei; Wu, Hua; Cheng, Zhen; 苏新辉; 吴华 (WILEY-BLACKWELL, 2013)
      Intraoperative fluorescence imaging especially near-infrared fluorescence (NIRF) imaging has the potential to revolutionize neurosurgery by providing high sensitivity and real-time image guidance to surgeons for defining ...
    • Imaging anatomy and variation of vertebral artery and bone structure at craniocervical junction 

      Duan, Shaoyin; Lv, Shaomao; Ye, Feng; Lin, Qingchi; 段少银 (EUR SPINE J, 2009-08)
      The objective of this article is to display the vertebral artery and bone structure at the craniocervical junction (CJVA and C(0-1-2)) with three-dimensional CT angiography (3DCTA) and identify their anatomic features and ...
    • Imaging integrin alpha(v)beta(3) positive glioma with a novel RGD dimer probe and the impact of antiangiogenic agent (Endostar) on its tumor uptake 

      Wu, Hua; Chen, Haojun; Sun, Yonghong; Wan, Ying; Wang, Fan; Jia, Bing; Su, Xinhui; 吴华; 苏新辉 (ELSEVIER IRELAND LTD, 2013-Jul 1)
      Integrin alpha(v)beta(3) has been recognized to play an important role in angiogenesis, tumor growth and metastasis. It will be of interest to apply this promising target for tumor imaging and visualization of tumor ...
    • Immunogenicity and safety of hepatitis E vaccine in healthy hepatitis B surface antigen positive adults 

      Wu, Ting; Huang, Shou-Jie; Zhu, Feng-Cai; Zhang, Xue-Feng; Ai, Xing; Yan, Qiang; Wang, Zhong-Ze; Yang, Chang-Lin; Jiang, Han-Min; Liu, Xiao-Hui; Guo, Meng; Du, Hai-Lian; Ng, Mun-Hon; Zhang, Jun; Xia, Ning-Shao; 吴婷; 杜海莲; 张军; 夏宁邵 (LANDES BIOSCIENCE, 2013)
      A recombinant hepatitis E vaccine, Hecolin (R), has been proven safe and effective in healthy adults. As hepatitis B surface antigen (HBsAg) positive individuals have a higher risk of poor prognosis after super-infection ...
    • Immunosuppressive effect of compound K on islet transplantation in a STZ-induced diabetic mouse model 

      Peng-Fei Ma; 马鹏飞; Jie Jiang; 姜杰; Chang Gao; Pan-Pan Cheng; Jia-Li Li; Xin Huang; Ying-Ying Lin; Qing Li; Yuan-Zheng Peng; 彭园征; Mei-Chun Cai; Wei Shao; 邵巍; Qi Zhu; Sai Han; Qing Qin; Jun-Jie Xia; 夏俊杰; Zhong-Quan Qi; 齐忠权 (American Diabetes Association, 2014-05-16)
      Islet transplantation is a therapeutic option for type 1 diabetes, but its long-term success is limited by islet allograft survival. Many factors imperil islet survival, especially the adverse effects and toxicity due to ...
    • Immunosuppressive properties of a series of novel inhibitors of the monocarboxylate transporter MCT-1 

      Pahlman, Clara; Qi, Zhongquan; Murray, Clare M.; Ferguson, Douglas; Bundick, Robert V.; Donald, David K.; Ekberg, Henrik; 齐忠权 (WILEY-BLACKWELL, 2013)
      We have recently described the immunosuppressive properties of AR-C117977 and AR-C122982, representatives of a group of compounds identified as inhibitors of lactate transporters (monocarboxylate transporters; MCTs). These ...
    • Implicit reading in Chinese pure alexia 

      Shan, Chunlei; Zhu, Renjing; Xu, Mingwei; Luo, Benyan; Weng, Xuchu; 朱仁敬 (BRAIN LANG, 2010-09)
      A number of recent studies have shown that some patients with pure alexia display evidence of implicit access to lexical and semantic information about words that they cannot read explicitly. This phenomenon has not been ...
    • Improved characteristics and protective efficacy in an animal model of E-coli-derived recombinant double-layered rotavirus virus-like particles 

      Li, Tingdong; Lin, Haijun; Zhang, Yue; Li, Min; Wang, Daning; Che, Yaojian; Zhu, Yinbin; Li, Shaowei; Zhang, Jun; Ge, Shengxiang; Zhao, Qinjian; Xia, Ningshao; 张悦; 张军; 葛胜祥; 赵勤俭; 夏宁邵 (ELSEVIER SCI LTD, 2014-04-07)
      Live rotavirus vaccines that are effective in middle- and high-income countries have been found to be less immunogenic and effective in infants in resource-limited settings. The virus-like particle (VLP) approach is promising ...
    • Improved controlled release study of lomustine 

      Sun, Y.; Zhou, H. Y.; Zhang, Q. Q.; Wu, X. Y.; 张其清 (2000)
      Lomustine(CCNU) microcapsules was prepared by improved recoacervation method, then mixed microcapsules with 0.7% collagen smelling solution to prepare the emulsion, spreaded the emulsion aln the plate to form membrane and ...
    • Improved photovoltaic performance of InGaN single junction solar cells by using n-on-p type device structure 

      方亚 (2010)
      The performance of In(0.65)Ga(0.35)N single junction solar cell including an InGaN window layer with p-on-n and n-on-p two types of configurations has been theoretically investigated. By taking polarization effects into ...