Now showing items 1-4 of 4
Camptothecin and cisplatin upregulate ABCG2 and MRP2 expression by activating the ATMUNF-kappa B pathway in lung cancer cells
(SPANDIDOS PUBL LTD, 2013)
Multidrug resistance (MDR) formation is an important problem in lung cancer chemotherapy. Our study showed that both camptothecin and cisplatin could not only induce ATM and NF-kappa B activation but also upregulate ...
Corilagin prevents tert-butyl hydroperoxide-induced oxidative stress injury in cultured N9 murine microglia cells
(NEUROCHEM INT, 2011-08)
Oxidative stress plays an important role in neurodegenerative diseases. Reactive oxygen species (ROS)-mediated stress in microglia in vivo could result in cellular injuries and preferentially induces neuronal injury. ...
Resveratrol Protects Mouse Oocytes from Methylglyoxal-Induced Oxidative Damage
(PUBLIC LIBRARY SCIENCE, 2013-Oct 2)
Methylglyoxal, a reactive dicarbonyl compound, is mainly formed from glycolysis. Methylglyoxal can lead to the dysfunction of mitochondria, the depletion of cellular anti-oxidation enzymes and the formation of advanced ...
Carboxylated single-walled carbon nanotubes induce an inflammatory response in human primary monocytes through oxidative stress and NF-kappa B activation
A mechanistic understanding of interactions between carbon nanotubes (CNTs) and living systems has become imperative owing to the growing nanomedicine applications and the mounting societal concerns on nanosafety. The ...