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dc.contributor.authorLi, Li
dc.contributor.authorZhou, Xiaopin
dc.contributor.authorChen, Xiaolin
dc.contributor.author陈小麟
dc.date.accessioned2012-08-10T11:53:08Z
dc.date.available2012-08-10T11:53:08Z
dc.date.issued2011
dc.identifier.citationJournal of Molecular Evolution,Volume 72, Numbers 5-6 (2011), 474-483zh_CN
dc.identifier.issn0022-2844
dc.identifier.urihttp://dx.doi.org/doi:10.1007/s00239-011-9446-3
dc.identifier.uriWOS:000293190900004
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/13463
dc.description.abstractMajor histocompatibility complex (MHC) is a multi-gene family that is very suitable to investigate a wide range of open questions in evolutionary ecology. In this study, we characterized two expressed MHC class II B genes (DAB1 and DAB2) in the Grey Heron (Aves: Ardea cinerea). We further developed the primer pairs to amplify and sequence two MHC class II B loci in ten ardeid birds. Phylogenetic analysis revealed that different parts of the genes showed different evolutionary patterns. The exon 2 sequences tended to cluster two gene-specific lineages. In each lineage, exon 2 sequences from several species showed closer relationships than sequences within species, and two shared identical alleles were found between species (Egretta sacra and Nycticorax nycticorax; Egretta garzetta and Bubulcus ibis), supporting the hypothesis of trans-species polymorphism. In contrast, the species-specific intron 2 plus partial exon 3 tree suggested that DAB1 and DAB2 were subject to concerted evolution. GENECONV analyses showed the gene exchange played an important role in the ardeid MHC evolution.zh_CN
dc.description.sponsorshipNational Natural Science Foundation of China[30970380, 40876077]; Fujian Natural Science Foundation of China[2009J01195, 2008S0007]; Program for Innovative Research Team in Science and Technology in Fujian Province Universityzh_CN
dc.language.isoenzh_CN
dc.publisherSPRINGERzh_CN
dc.subjectMHC II B genezh_CN
dc.subjectArdeid birdszh_CN
dc.subjectTrans-species polymorphismzh_CN
dc.subjectConcerted evolutionzh_CN
dc.subjectGenetic exchangezh_CN
dc.titleCharacterization and Evolution of MHC Class II B Genes in Ardeid Birdszh_CN
dc.typeArticlezh_CN


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