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A new approach to (-)-anisomycin

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A new approach to (-)-anisomycin.htm (407bytes)
Date
2006-10-04
Author
Huang, PQ
黄培强
Wang, SL
Ruan, YP
阮源萍
Gao, JX
高景星
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  • 化学化工-已发表论文 [14469]
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Abstract
(R)-(-)-1-Benzyloxycarbonyl-2-(4-methoxyphenyl)methyl-3-pyrroline (16) was prepared from (S)-malic acid. The key steps involved a highly regio and trans stereoselective reductive alkylation of N-benzylmalimide (4). This constitutes a formal asymmetric synthesis of natural (-)-anisomycin (2).
Citation
NATURAL PRODUCT LETTERS,1998,11(2):101-106
URI
http://dx.doi.org/doi:10.1080/10575639808041204
https://dspace.xmu.edu.cn/handle/2288/13397

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