A new approach to (-)-anisomycin
Date
2006-10-04Author
Huang, PQ
黄培强
Wang, SL
Ruan, YP
阮源萍
Gao, JX
高景星
Collections
- 化学化工-已发表论文 [14469]
Abstract
(R)-(-)-1-Benzyloxycarbonyl-2-(4-methoxyphenyl)methyl-3-pyrroline (16) was prepared from (S)-malic acid. The key steps involved a highly regio and trans stereoselective reductive alkylation of N-benzylmalimide (4). This constitutes a formal asymmetric synthesis of natural (-)-anisomycin (2).