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dc.contributor.advisor李庆阁
dc.contributor.author曾小红
dc.date.accessioned2017-06-20T08:37:11Z
dc.date.available2017-06-20T08:37:11Z
dc.date.issued2017-03-23
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/133730
dc.description.abstract结核病是当今世界范围内对人类健康最具威胁的传染性疾病之一,具有潜伏感染的特点,因此追踪传染源和查证传播途径是长期困扰结核病流行病学研究的一个问题,也是分子流行病学要解决的首要问题。基因分型技术是分子流行病学研究的一个有力工具,在研究结核病传播规律方面有着不可替代的优势。一个理想的基因分型技术应当具备简便、快速、结果可在不同实验室间进行比较等特点。本论文基于探针熔解曲线分析技术,建立新型的快速结核分枝杆菌分型体系,并评价其临床应用。论文内容如下: 第一章为绪论,首先概述了结核病目前的流行情况,阐述了结核分枝杆菌的分子分型技术及其在结核病防控中的作用,介绍了本论文所采用的探针熔解曲线分析技术,最...
dc.description.abstractTuberculosis (TB) is still a leading cause of death among infectious diseases worldwide. Tracking and transmission of Mycobacterium tuberculosis by traditional contact investigation is limited due to the long latent period of Mycobacterium tuberculosis. Genotyping is used to track specific isolates of Mycobacterium tuberculosis in a community. It has been successfully used in molecular epidemiolog...
dc.language.isozh_CN
dc.relation.urihttps://catalog.xmu.edu.cn/opac/openlink.php?strText=55135&doctype=ALL&strSearchType=callno
dc.source.urihttps://etd.xmu.edu.cn/detail.asp?serial=58572
dc.subject结核分枝杆菌
dc.subject熔解曲线分析
dc.subjectSpoligotyping
dc.subject耐药
dc.subjectMycobacterium tuberculosis
dc.subjectmelting curve analysis
dc.subjectSpoligotyping
dc.subjectdrug-resistance
dc.title新型结核分枝杆菌间隔子寡核苷酸分型及临床评价
dc.title.alternativeA New Type of Spacer Oligonucleotide Typing for Mycobacterium Tuberculosis Complex and Clinical Evaluation
dc.typethesis
dc.date.replied2016-05-20
dc.description.note学位:理学博士
dc.description.note院系专业:生命科学学院_生物化学与分子生物学
dc.description.note学号:21620120153779


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