Show simple item record

dc.contributor.authorYe, Wenduo
dc.contributor.authorLin, Wenbo
dc.contributor.authorTartakoff, Alan M.
dc.contributor.authorTao, Tao
dc.contributor.author陶涛
dc.date.accessioned2012-04-07T09:40:06Z
dc.date.available2012-04-07T09:40:06Z
dc.date.issued2011-01-20
dc.identifier.citationBiochimica et Biophysica Acta (BBA) - Molecular Cell Research Volume 1813, Issue 9, September 2011, Pages 1654–1662zh_CN
dc.identifier.issn0167-4889
dc.identifier.urihttp://dx.doi.org/doi:10.1016/j.bbamcr.2011.01.013
dc.identifier.uriWOS:000294032300009
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/12004
dc.description.abstractHomeodomain proteins are crucial transcription factors for cell differentiation, cell proliferation and organ development. Interestingly, their homeodomain signature structure is important for both their DNA-binding and their nucleocytoplasmic trafficking. The accurate nucleocytoplasmic distribution of these proteins is essential for their functions. We summarize information on (a) the roles of karyopherins for import and export of homeoproteins, (b) the regulation of their nuclear transport during development, and (c) the corresponding complexity of homeoprotein nucleocytoplasmic transport signals. This article is part of a Special Issue entitled: Regulation of Signaling and Cellular Fate through Modulation of Nuclear Protein Import. (C) 2011 Elsevier B.V. All rights reserved.zh_CN
dc.description.sponsorshipNational Foundation of Science of China[30971669, 81071670]; Ministry of Science and Technology, China[2006AA02A310]; Ministry of Education, China[20090121110014]; Department of Science and Technology, Fujian Province China[2009I0026]; National Institutes of Healthzh_CN
dc.language.isoenzh_CN
dc.publisherELSEVIER SCIENCE BVzh_CN
dc.subjectHomeodomainzh_CN
dc.subjectHomeoproteinzh_CN
dc.subjectNuclear transportzh_CN
dc.subjectImportin alphazh_CN
dc.subjectKaryopherin betazh_CN
dc.subjectNLSzh_CN
dc.subjectNESzh_CN
dc.subjectDevelopmentzh_CN
dc.subjectRegulationzh_CN
dc.titleKaryopherins in nuclear transport of homeodomain proteins during developmentzh_CN
dc.typeArticlezh_CN


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record