Show simple item record

dc.contributor.authorShao, Zongze
dc.contributor.authorLai, Qiliang
dc.contributor.authorZhong, Huanzi
dc.contributor.authorWang, Jianning
dc.contributor.authorYuan, Jun
dc.contributor.authorSun, Fengqin
dc.contributor.authorWang, Liping
dc.contributor.authorZheng, Tianling
dc.contributor.author郑天凌
dc.date.accessioned2012-03-29T08:29:19Z
dc.date.available2012-03-29T08:29:19Z
dc.date.issued2010-09-17
dc.identifier.citationInt J Syst Evol Microbiol. 2011 Sep;61(Pt 9):2040-4.zh_CN
dc.identifier.issn1466-5026
dc.identifier.urihttp://dx.doi.org/doi:10.1099/ijs.0.023168-0
dc.identifier.uriWOS:000295432300003
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/11928
dc.description.abstractMethyl parathion (MP) is a widely used organophosphorus pesticide, which has been related to a broad spectrum of toxic effects on environmental organisms. The present study investigated the changes in the protein profile of enriched membrane fraction from zebrafish (Danio rerio) brain exposed to three concentrations (0.5, 1 and 2 mg/L) of MP. 2-DE revealed that the abundance of 21 protein spots was significantly changed by MP stress. By matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and database search, 16 protein spots were identified as membrane proteins, among which 8 were down-regulated, while 8 were up-regulated. These proteins are mainly involved in oxidative stress response, signal transduction, metabolism, protein synthesis and degradation, neuroplasticity and regeneration as well as synaptic transmission. These results may aid our understanding of the mechanism of MP-induced neurotoxicity and provide the possibility of the establishment of candidate biomarkers of MP.zh_CN
dc.description.sponsorshipNational Infrastructure of Natural Resources for Science and Technology Program of China[2005DKA21209]; National Natural Science Foundation of China[40906083]; Scientific Research Foundation of Third Institute of Oceanography, State Oceanic Administration[2009065]zh_CN
dc.language.isoenzh_CN
dc.publisherSOC GENERAL MICROBIOLOGYzh_CN
dc.titleRoseovarius indicus sp nov., isolated from deep-sea water of the Indian Oceanzh_CN
dc.typeArticlezh_CN


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record