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dc.contributor.authorZhang, Zhubao
dc.contributor.authorYan, Xiaowen
dc.contributor.authorXu, Ming
dc.contributor.authorYang, Limin
dc.contributor.author杨利民
dc.contributor.authorWang, Qiuquan
dc.contributor.author王秋泉
dc.date.accessioned2012-03-23T01:37:49Z
dc.date.available2012-03-23T01:37:49Z
dc.date.issued2011-04-01
dc.identifier.citationJOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY,2011,26(6):1175-1177zh_CN
dc.identifier.issn0267-9477
dc.identifier.urihttp://dx.doi.org/doi:10.1039/c1ja00010a
dc.identifier.uriWOS:000290999000006
dc.identifier.urihttps://dspace.xmu.edu.cn/handle/2288/11849
dc.description.abstractIn this proof-of-concept study, a novel dual-labelling strategy for conjugating -SH and -NH(2) of a peptide was developed, in which an element tag (1,4,7,10-tetraazacyclododecane-1,4,7-trisacetic acid-10-maleimidoethylacetamide loaded with europium) and a fluorescent tag (fluorescein isothiocycanate) were employed. Its feasibility was demonstrated using HPLC-UV/ESI-MS for evaluating labelling-efficiency and HPLC-ICPMS with (153)Eu isotope dilution as well as CE-LIF for the determination of peptides.zh_CN
dc.description.sponsorshipNational Natural Science Foundation of China[21035006, 20775062]; 973 National Basic Research Program[2009CB421605]zh_CN
dc.language.isoenzh_CN
dc.publisherROYAL SOC CHEMISTRYzh_CN
dc.titleA dual-labelling strategy for integrated ICPMS and LIF for the determination of peptideszh_CN
dc.typeArticlezh_CN


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