A novel anti-interference and pH-modulation device: application to enzyme-free glucose detection
Date
2011Author
Su, Yuhua
Hu, Rongzong
胡荣宗
Huang, Weixiong
Hu, Kangkang
Collections
- 化学化工-已发表论文 [14469]
Abstract
We report on a novel anti-interference and pH-modulation device (herein after referred to as "device"). It is based on electrodialysis and can continuously increase the pH value of the carrier solution and - at the same time - remove interfering analytical signals obtained for ascorbic acid (AA) and uric acid (UA). The "device" was coupled to the FIA-amperometric detection of glucose. The linear range is from 1 mu mol L(-1) to 0.4 mmol L(-1), with a sensitivity of 213 mu A cm(-2) mM(-1) and a detection limit of 1 mu mol L(-1) at a signal-to-noise ratio of 3. The method was used to sucessfully determine glucose in serum. This study represents a novel technique for overcoming analytical interference and is expected to find applications in liquid chromatography, for example in on-line pH-modulation if different pH values are needed for separation and detection.
Citation
MICROCHIMICA ACTA,2011,173(1-2):19-26URI
http://dx.doi.org/doi:10.1007/s00604-010-0501-3WOS:000290522800003
https://dspace.xmu.edu.cn/handle/2288/11712