Functionalized Silica Nanotubes As Affinity Matrices for Bilirubin Removal
- 化学化工－已发表论文 
Arginine-immobilized silica nanotubes as affinity matrices were fabricated for bilirubin removal. The silica nanotubes were prepared by depositing silica within the alumina membrane through sol-gel method. Ligand arginine was immobilized on the inner and outer surfaces of silica nanotubes by activating with glutaraldehyde. The content of arginine of affinity matrices was similar to 20.1 mg/g nanotubes. Such arginine-immobilized affinity matrices were used to adsorb bilirubin from the bilirubin-phosphate solution and bilirubin-albumin solution. The effects of temperature, ionic strength, albumin concentration, and the adsorption mechanism were investigated by batch experiments. The results showed arginine-immobilized silica nanotubes achieved excellent adsorption capacity for bilirubin (similar to 63.6 mg/g nanotubes).
CitationIEEE TRANSACTIONS ON NANOTECHNOLOGY，2011,10（3）：626-631