Inhibition by polycyclic aromatic hydrocarbons of ATPase activities in Sebastiscus marmoratus larvae: Relationship with the development of early life stages
- 生命科学－已发表论文 
Sebastiscus marmoratus larvae were exposed to waterborne polycyclic aromatic hydrocarbons (PAHs) containing 3-5 rings, benzo[a]pyrene (BaP), pyrene (Py) or phenanthrene (Pile), respectively at 0.01, 0.1 and 1 mu g L(-1). Cumulative mortality, frequency of dorsal curvature and rate of pericardial and yolk sac edema in larvae treated for 8 days were significantly increased in a dose-dependent manner. All three PAHs resulted in reduction of the lower jaw, and the extent of reduction increased with increasing concentrations of the PAHs. Na(+)/K(+)-ATPase and Ca(2+)-ATPase activity in larvae exposed to the three PAHs were all significantly inhibited in a dose-dependent manner. Analysis using the Pearson correlation coefficient indicated a significant correlation between the rate of the dorsal curvature and edema and the inhibition of Na(+)/K(+)-ATPase and Ca(2+)-ATPase activity, suggesting that the developmental defects caused by PAHs were related to their inhibition of Na(+)/K(+)-ATPase and Ca(2+)-ATPase activity. (C) 2010 Elsevier Ltd. All rights reserved.
CitationMarine Environmental Research 2011,Vol.4 Issue(4):86-90