Highly efficient iridium catalyst for asymmetric transfer hydrogenation of aromatic ketones under base-free conditions
Date
2005-02Author
Zhen-Rong Dong
Yan-Yun Li
Jian-Shan Chen
Bao-Zhu Li
Yan Xing
Jing-Xing Gao
高景星
Collections
- 化学化工-已发表论文 [14469]
Abstract
Catalytic systems generated in situ from the chiral PNNP ligands with iridium or rhodium hydride complexes exhibited excellent catalytic activity and good enantioselectivity in the asymmetric transfer hydrogenation of aromatic ketones without added base. The best result was obtained in the lrH(CO)(PPh3)(3)-ligand 2 catalytic system with up to 99% yield and 97% ee.