Detailed studies on the enantioselective synthesis and HPLC enantioseparation of N-protected 3-hydroxyglutarimides
发布日期
2005-09作者
Yuan-Ping Ruan
阮源萍
Bang-Guo Wei
Xiu-Qing Xu
Gang Liu
De-Sheng Yu
Liang-Xian Liu
Pei-Qiang Huang
黄培强
所在专题
- 化学化工-已发表论文 [14469]
摘要
An analytical HPLC method using CHIREX (S)-LEU/(S)-alpha-NEA column was developed for the determination of the enantiomeric excesses of N-protected (S)-3-hydroxyglutarimides. Using this method, detailed studies on the base-promoted ring-expansion reaction of the amidolactones, derived from L-glutamic acid, were undertaken.