Inhibitory effects on mushroom tyrosinase by p-alkoxybenzoic acids
- 生命科学－已发表论文 
The inhibitory kinetics of the diphenolase of mushroom tyrosinase by seven p-alkoxybenzoic acids has been studied. The results show that these derivatives of benzoic acid behave as reversible inhibitors. Among them, p-hydroxybenzoic acid is competitive, while p-methoxybenzoic acid is non-competitive, p-ethoxybenzoic acid is mixed-II type, and the rest all behave as classical uncompetitive inhibitors. The inhibition constants of all of the seven compounds assayed, characterizing the inhibition, were evaluated. The models of the interactions between the enzyme and the inhibitors are compared. (C) 2004 Elsevier Ltd. All rights reserved.
CitationFood Chemistry，Volume 91, Issue 2, June 2005, Pages 269-274