Effects of biogenic amines on the testicular development in mud crabs Scylla serrata

Abstract

A new lactone (1), named musellactone, was isolated from the aerial parts of Musella lasiocarpa, along with eight known compounds. The structures were chemically characterized by spectroscopic methods. Musellactone (1), and 2-methyl-9-(4'-hydroxyphenyl)-phenalen-1-one (2), showed different effects against five bacteria strains, and 1,2,3,4-tetrahydro-1,2-dimethyl-6,7-isoquinolinediol (3), showed significant cytotoxic activities in vitro against KB, HL-60 and BEL-7404 human carcinoma cell lines.