超快速COSY类2DNMR实验弛豫假峰的抑制

Abstract

在脉冲梯度场基础上研究了进一步缩短COSy类2dnMr实验数据采集时间的新方法.利用主动屏蔽梯度场线圈的梯度场恢复时间仅为100μS数量级这一特点，提出一类基于脉冲梯度场消除弛豫假峰的脉冲序列.并以dQf-COSy脉冲序列为例加以验证.实验结果表明：采用文中的方法，取序列重复时间远小于T＿1和T＿2是切实可行的；梯度场技术能很好地抑制弛豫假蜂以达到2dnMk数据的快速采集.

In this paper，pulsed Field gradients are used to suppress the rapid－pulsing artiFacts．Due to its superior homospoil charactersitic，pulsed Field gradients ofFer an important method For removal of artiFacts when data is being acquired Fast compared to the relaxation times of the nuclei under study．The experimential results show that the quality of DQF－COSY spectra can be improved by the modiFied pulsc sequence，and the pulsed Field gradients provide a good method For ultra－rapid acquisition 2D COSY－like NMR experiments with suppression the repetition rate artiFacts.