Tuberculariols A-C, New Sesquiterpenes from the Mutant Strain M-741 of Tubercularia sp TF5

Abstract

Three new sesquiterpenes, tuberculariols A-C(1-3, resp.), were isolated from the mutant strain M-741 of Tubercularia sp. TF 5, an endophytic fungus of Taxus mairei. Their structures were elucidated by spectroscopic analyses including 1D- and 2D-NMR experiments, and HR-Q-TOF-MS. Antitumor and antibacterial properties of these compounds were evaluated.