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Three New ent-Trachylobane Diterpenoids from Co-cultures of the Calli of Trewia nudiflora and Fusarium sp WXE

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Three New ent-Trachylobane Diterpenoids from Co-cultures of the Calli of Trewia nudiflora and Fusarium sp WXE.htm (413bytes)
Date
2009
Author
Wu, Xin
Lu, Chun-Hua
Shen, Yue-Mao
沈月毛
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  • 生命科学-已发表论文 [5901]
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Abstract
Five diterpenoids, including three new ent-trachylobane diterpenoids, i.e., (3 alpha)-3-hydroxy-ent-trachylobane-17,19-dioic acid 19-methyl ester (1), ent-trachylobane-17,19-dioic acid 19-methyl ester (2), ent-trachylobane-17,19-dioic acid (3), and two known atisane-type ones, i.e., (16 alpha)-16,17-dihydroxy-ent-atisan-19-oic acid methyl ester (4), and 17-hydroxy-ent-atisan-19-oic acid methyl ester (5), were isolated from the co-culture extract of the calli of Trewia nudiflora and its endophytic fungus Fusarium sp. WXE. Their structures were elucidated by spectroscopic analyses, including 1D- and 2D-NMR experiments, and HR-Q-TOF mass spectrometry. The antitumor and antibacterial properties of the new compounds were evaluated.
Citation
Helvetica Chimica Acta,Volume92,Issue12,pages2783-2789,December2009
URI
http://dx.doi.org/doi:10.1002/hlca.200900168
https://dspace.xmu.edu.cn/handle/2288/10134

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