Now showing items 1-5 of 5

    • A bacterially expressed particulate hepatitis E vaccine: antigenicity, immunogenicity and protectivity on primates 

      Li, SW; 李少伟; Zhang, J; 张军; Li, YM(Beijing Wantai Biological Pharmacy Enterprise Co., ); Ou, SH; Huang, GY(Center of Disease Control, Guangxi Autonomous Region); He, ZQ; Ge, SX; 葛胜祥; Xian, YL(Beijing Wantai Biological Pharmacy Enterprise Co., ); Pang, SQ(Beijing Wantai Biological Pharmacy Enterprise Co.); Ng, MH; Xia, NS; 夏宁邵 (ELSEVIER SCI LTD, 2005)
      It was evaluated its antigenicity, immunogenicity and efficacy of a candidate recombinant hepatitis E virus (HEV) vaccine, referred hitherto as HEV 239 vaccine. The vaccine peptide has a 26 amino acids extension from the ...
    • Difference of T cell and B cell activation in two homologous proteins with similar antigenicity but great distinct immunogenicity 

      Wu, Ting; Wu, Xiao-lu; Ou, Shan-hai; Lin, Chun-xin; Cheng, Tong; Li, Shao-wei; Ng, Mun Hon; Zhang, Jun; 张军; Xia, Ning-shao; 夏宁邵 (PERGAMON-ELSEVIER SCIENCE LTD, 2007)
      The candidate particulate hepatitis E vaccine, HEV 239, has been shown to be an efficacious vaccine in primates, and clinical study to date shows it to be safe and irnmunogenic for humans. The antigenicity of HEV 239 is ...
    • Identification of novel immunogenic proteins of Shigella flexneri 2a by proteomic methodologies 

      Peng, XX; 彭宣宪; Ye, XT; Wang, SY; 王三英 (ELSEVIER SCI LTD, 2004)
      Shigella spp. are one of the most important etiological factors for people who are living in developing countries and travelers to tropical countries. High priority has been given by the World Health Organization to the ...
    • Rapid screening of highly efficient vaccine candidates by immunoproteomics 

      Chen, ZJ; Peng, B;; Wang, SY; 王三英; Peng, XX; 彭宣宪 (WILEY-V C H VERLAG GMBH, 2004)
      Diseases caused by microorganisms can be controlled by vaccines, which require neutralizing antigens. Therefore, it is very important to identify highly efficient immunogens for immune prevention. By combining immunoproteomics ...
    • 科学监管提高疫苗可及性 

      陈思伊; 张彩; 黄小芬; 王鑫; 赵勤俭 (2017)
      疫苗储存运输要遵循冷链运输(cold; chain,CC)的要求,这很大程度上限制了疫苗的接种和普及,尤其是在那些贫困偏远地区。为扩大疫苗可及性,世界卫生组织(World Health; Organization,WHO)于2012年首次提出了受控温度链(controlled temperature; chain,CTC)法规,即在政府部门和WHO的监管下,在有充分热稳定性数据支持的前提下,若申报CTC的疫苗在不低于40 ℃下存放至少3; ...