Now showing items 366-385 of 5878

    • Bacteria expressed hepatitis E virus capsid proteins maintain virion-like epitopes 

      Wei, Minxi; Zhang, Xiao; Yu, Hai; Tang, Zi-Min; Wang, Kaihang; Li, Zhongyi; Zheng, Zizheng; Li, Shaowei; Zhang, Jun; Xia, Ningshao; Zhao, Qinjian; 俞海; 郑子峥; 李少伟; 张军; 夏宁邵; 赵勤俭 (ELSEVIER SCI LTD, 2014-05-19)
      The protein encoded by ORF2 in hepatitis E virus (HEV) is the only capsid protein for this single-stranded RNA virus. It was previously shown that 148 aa (aa 459-606) was needed for dimer formation, whereas 239 aa (aa ...
    • Bacterial community dynamics during a bloom caused by Akashiwo sanguinea in the Xiamen sea area, China 

      Yang, Caiyun; Li, Yi; Zhou, Yanyan; Zheng, Wei; Tian, Yun; Zheng, Tianling; 田蕴 (2012-12)
      Phytoplankton blooms are a worldwide ecological problem and one of the major algae that cause phytoplankton blooms is Akashiwo sanguinea. Though much research has addressed the abiotic causes (e.g. growth condition) of A. ...
    • Baifuzi reduces transient ischemic brain damage through an interaction with the STREX domain of BKCa channels 

      Chi, S.; Cai, W.; Liu, P.; Zhang, Z.; Chen, X.; Gao, L.; Qi, J.; Bi, L.; Chen, L.; Qi, Z.; 陈亮 (2010-01)
      Stroke is a long-term disability and one of the leading causes of death. However, no successful therapeutic intervention is available for the majority of stroke patients. In this study, we explored a traditional Chinese ...
    • Bak基因的克隆、测序及表达 

      温龙平; 陈亚兵; 俞春东; 蔡毓; 曾桂生; 曾定 (1995)
      bCl-2蛋白家族在细胞编程死亡的调控中起重要的作用。本文报导了bCl-2家族新成员bAk的克隆、测序及其在大肠杆菌中的表达过程,为研究细胞编程死亡以及bAk在其中的作用机制提供了重要的依据。
    • BASIC AND TRANSLATIONAL-PANCREAS 

      Gao, Tao; Zhou, Dawang; Yang, Chenghua; Singh, Tarjinder; Penzo-Mendez, Alfredo; Maddipati, Ravikanth; Tzatsos, Alexandros; Bardeesy, Nabeel; Avruch, Joseph; Stanger, Ben Z.; 周大旺 (W B SAUNDERS CO-ELSEVIER INC, 2013)
      BACKGROUND & AIMS: The Hippo signaling pathway is a context-dependent regulator of cell proliferation, differentiation, and apoptosis in species ranging from Drosophila to humans. In this study, we investigated the role ...
    • Basigin expression and hormonal regulation in mouse uterus and embryos during the peri-implantation period 

      Xiao, L. J.; Chang, H.; Ding, N. Z.; Kadomatsu, K.; Yang, Z. M.; 杨增明 (2001)
      a transmembrane glycoprotein belonging to the immunoglobulin superfamily, has been shown to be essential for implantation and fertilization. The aim of this study was to determine basigin expression and hormonal regulation ...
    • Basigin expression and hormonal regulation in mouse uterus during the peri-implantation period 

      Xiao, L. J.; Chang, H.; Ding, N. Z.; Ni, H.; Kadomatsu, K.; Yang, Z. M.; 杨增明 (2002)
      Basigin, a transmembrane glycoprotein belonging to the immunoglobulin superfamily, has been shown to be essential for fertilization and implantation. The aim of this study was to determine the expression and hormonal ...
    • Basigin expression and hormonal regulation in the rat uterus during the peri-implantation period 

      Xiao, L. J.; Diao, H. L.; Ma, X. H.; Ding, N. Z.; Kadomatsu, K.; Muramatsu, T.; Yang, Z. M.; 杨增明 (2002)
      Basigin is essential for fertilization and implantation. The aim of this study was to determine the expression and hormonal regulation of the basigin gene in the rat uterus during the peri-implantation period. Basigin mRNA ...
    • Basigin expression and regulation in mouse ovary during the sexual maturation and development of corpus luteum 

      Chang, H.; Ni, H.; Ma, X. N.; Xu, L. B.; Kadomatsu, K.; Muramatsu, T.; Yang, Z. M.; 杨增明 (2004)
      Basigin is a highly glycosylated transmembrane protein belonging to the immunoglobulin superfamily. Basigin-deficient male mice are azoospermic. The majority of basigin null embryos die around the time of implantation. ...
    • Bax基因cDNA的分子克隆研究 

      曾桂生; 陈亚兵; 陈华; 俞春东; 蔡毓; 温龙平 (1996)
      细胞编程死亡(PrOgrAMEdCElldEATH)是细胞生理性死亡的一种主要形式。bAX具有抑制细胞编程死亡的作用。本研究采用PCr方法,从人肿瘤细胞Hl—60CdnA文库中扩增出若干个bAXCdnA片段,然后将它们分别与PgEM—T测序质粒载体连接,并转化到大肠杆菌JM109中去。用蓝/白法筛选重组菌落,经酶切分析及PCr鉴定,获得了插入片段大小约为0.4kb及1.1kb的bAXCdnA重组质粒PbAXl和PbAX2。这些片段的测序 ...
    • bax基因促进细胞编程死亡的机理研究 

      曾桂生; 陈亚兵; 温龙平; 俞春东; 蔡毓 (1996)
      bAX基因促进细胞编程死亡的机理研究曾桂生,陈亚兵,温龙平,俞春东,蔡毓(厦门大学肿瘤细胞工程国家专业实验室厦门361005)1980年WyllIEA.H.等通过糖皮激素诱导胸腺细胞死亡的实验,提出了细胞编程死亡(PrOgAMMEdCElldEATH...
    • Bc1-2基因加强表达对OA诱发的细胞编程死亡的效应 

      温龙平; 蔡毓; 陈亚兵; 俞春东; 曾桂生 (1997)
      OA能诱发人神经母细胞瘤Sk细胞进行编程死亡.死亡细胞缩小变圆,细胞质凝聚,dnA有控降解成约200bP左右的片段,且这一过程可由蛋白质合成抑制剂亚胺环己酮(CHX)抑制.将编码bC1-2全长蛋白质的CdnA植入PXJ41nEO载体中,使其表达由HCMV病毒启动子控制.形成的顺义(PbCl-2-S)及反义(PbCl-2-AS)表达质粒经转染导入Sk细胞中获得稳定转染子,WEST-Ern印迹表明顺义转染子表达较大量的26kdbC1-2蛋白 ...
    • Bcl-2基因与细胞编程死亡 

      陈亚兵; 温龙平 (1994)
      细胞编程死亡在生物体的发育形成及功能维持中起着重要作用。本文着重介绍bCl-2基因及其产物对细胞编程死亡的抑制,探讨了bCl-2基因的作用机制,指出bCl-2基因的研究有重大的理论意义及应用前景。
    • Bcl-2基因加强表达对SK细胞编程死亡的效应 

      温龙平; 陈亚兵; 蔡毓; 曾桂生; 俞春东; 曾定 (1996)
      Tnf和OA诱发人神经母细胞瘤Sk细胞编程死亡(PCd)。将编码bCl-2完整蛋白质的CdnA植入PXJ41nEO载体中,由HCMV病毒启动子控制其表达。形成的正向(PbCl-2-S)及反向(PbCl-2-AS)表达质粒经转染导入Sk细胞中获得稳定转染子。WESTErn印迹表明正向转染子表达较大量的26kdbCl-2蛋白,而反向转染子则不表达。增强表达的bCl-2基因产物能抑制由Tnf引发的PCd,但不影响由OA引发的PCd,从而证明b ...
    • Bcl—2基因表达对TNF及OA诱发的细胞编程死亡的不同效应 

      陈亚兵; 蔡毓; 温龙平 (1996)
      用Tnf和OA(OkAdAICACId)诱发人神经母细胞瘤Sk细胞死亡,并证明细胞死亡为编程死亡(PrOgrMMEdCElldEATH,简称PCd)。将编码bCl-2全长蛋白的CdnA植入PJX41nEO载体中,使其表达由HCMV病毒起动子控制。形成的顺义(PbCl-2-S)及反义(PbCl-2-AS)表达质粒经转染导入Sk细胞中获得稳定转染子。WESTErn印迹表明顺义转染子表达大量的26kdbCl-2蛋白,而反义转染子则不表达。增强 ...
    • BEAM TESTS OF THE ZEUS BARREL CALORIMETER 

      陈亮 (1993)
      A fully compensating uranium-scintillator calorimeter was constructed for the ZEUS detector at HERA. Several of the barrel calorimeter modules were subjected to beam tests at Fermilab before shipping them to DESY for ...
    • Beneficial effects of Bacillus licheniformis on the intestinal microflora and immunity of the white shrimp, Litopenaeus vannamei 

      Li, Ke; Zheng, Tianling; 郑天凌; Tian, Yun; 田蕴; Xi, Feng; Yuan, Jianjun; Zhang, Guozheng; Hong, Huasheng (SPRINGER, 2007)
      When Bacillus licheniformis was administered to the white shrimp, Litopenaeus vannamei, although the total bacterial counts in the intestinal tract of the shrimp remained constant, Vibrio numbers significantly decreased ...
    • Benefit of radiotherapy for 90 patients with resected intrahepatic cholangiocarcinoma and concurrent lymph node metastases 

      陈奕欣 (2010)
      To evaluate the role of radiotherapy for patients with resected intrahepatic cholangiocarcinoma with concurrent macroscopic abdominal lymph node metastases. We identified 90 patients with resected intrahepatic cholangiocarcinoma ...
    • Benzo[a]pyrene exposure influences the cardiac development and the expression of cardiovascular relative genes in zebrafish (Danio rerio) embryos 

      Huang, Lixing; Wang, Chonggang; 王重刚; Zhang, Youyu; Li, Jian; Zhong, Yuanfu; Zhou, Yulin; Chen, Yixin; 陈奕欣; Zuo, Zhenghong; 左正宏 (PERGAMON-ELSEVIER SCIENCE LTD, 2012-04)
      It is reported that the most abundant polycyclic aromatic hydrocarbons (PAHs) in weathered crude oils are cardiotoxic. However, the action mechanism of PAHs on vertebrate cardiovascular development and disease is unclear. ...
    • Benzothiazoline based chemodosimeters for fluorogenic detection of hypochlorous acid 

      Wu, Zhisheng; Wu, Xuanjun; Li, Zhu; Yang, Yuhui; Han, Jiahuai; Han, Shoufa; 韩家淮; 韩守法 (PERGAMON-ELSEVIER SCIENCE LTD, 2013-Aug 1)
      Two nonfluorescent and colorless chemodosimeters featuring benzothiazoline moiety were developed for chromo-fluorogenic detection of HOCl. (C) 2013 Elsevier Ltd. All rights reserved.