显示条目: 21-40 / 166236

    • 1 ‘ S-1 ‘-Acetoxychavicol acetate isolated from Alpinia galanga inhibits human immunodeficiency virus type 1 replication by blocking Rev transport 

      Ye, Y; 叶勇; Li, B (2006-07)
      AIDS remains a major global health concern. Despite a number of therapeutic advancements, there is still an urgent need to develop a new class of therapy for human immunodeficiency virus (HIV). Here, it was shown that ...
    • 1%苯酚甘油在不同贮存条件下稳定性考察 

      方水凉; 连春福 (2013-09-15)
      目的考察苯酚甘油稳定性的影响因素,探讨其合理的贮存使用条件。方法通过苯酚甘油在不同贮存条件下的稳定性做试验,观察其外观性状、含量测定变化。结果温度和光照对苯酚甘油均有影响,光照的影响更大。结论苯酚甘油在冰箱(6±2)℃避光冷藏和室温(25±2)℃避光贮存12个月,其含量符合规定,质量稳定。
    • (1)H NMR-based metabonomics study of urine and serum samples from diabetic db/db mice 

      Xu, Jingjing; Cao, Hongting; Dong, Jiyang; 董继扬; Cai, Shuhui; Chen, Zhong (2009)
      A metabonomics approach based on high resolution (1)H NMR spectroscopy was applied to investigate the metabolite fingerprints in urine and serum samples from db/db mice of 8 weeks old, an animal model of type 2 diabetes ...
    • (1)H, (13)C, (15)N backbone and side-chain resonance assignments of the human Raf-1 kinase inhibitor protein 

      Yi, Cuiying( Chinese Acad Sci, Shanghai Inst Mat Med); Peng, Yu( Chinese Acad Sci, Shanghai Inst Mat Med); Guo, Chenyun; Lin, Donghai; 林东海 (SPRINGER, 2011)
      Raf-1 kinase inhibitor protein (RKIP) plays a pivotal role in modulating multiple signaling networks. Here we report backbone and side chain resonance assignments of uniformly (15)N, (13)C labeled human RKIP.
    • (1)H-NMR-based metabonomic analysis of metabolic profiling in diabetic nephropathy rats induced by streptozotocin 

      Zhao, Liangcai( Guangxi Med Univ, Affiliated Hosp 1); Gao, Hongchang( Wenzhou Med Coll, Sch Pharm); Lian, Fulin( Chinese Acad Sci, Shanghai Inst Mat Med); Liu, Xia( Chinese Acad Sci, Shanghai Inst Mat Med); Zhao, Yongxiang( Guangxi Med Univ, Affiliated Hosp 1); Lin, Donghai; 林东海 (AMER PHYSIOLOGICAL SOC, 2011-01)
      Zhao L, Gao H, Lian F, Liu X, Zhao Y, Lin D. (1)H-NMR-based metabonomic analysis of metabolic profiling in diabetic nephropathy rats induced by streptozotocin. Am J Physiol Renal Physiol 300: F947-F956, 2011. First published ...
    • “1+X”--我国社区矫正运行机制之选择 

      李艳 (2012-09-25)
      2011年2月25日新发布的《刑法修正案(八)》首次明确提出了“社区矫正”概念,并在管制、缓刑、假释刑中做出相应规定。2012年3月14日颁布的《刑事诉讼法修正案》与此遥相呼应,规定了“被判处管制、宣告缓刑、假释或者暂予监外执行的罪犯,依法实行社区矫正,由社区矫正机构负责执行。”立法的完善,使社区矫正的实施变得有法可依,在此基础上,迫切需要选择适合我国国情的社区矫正运行模式,为社区矫正的运行提供行之有效的机制保障。故笔者在对“上海模式” ...
    • 1,1'-Ureylenedi-7,7-dimethylbicyclo 221 heptan-2-one 

      Gao, Y. X.; Liu, P.; Fang, Y. X.; Tang, G.; Zhao, Y. F.; 赵玉芬 (2007-10)
      The title compound, C19H28N2O3, was obtained by the acidic hydrolysis of (1S,4R)-1-isocyanato-7,7-dimethylbicyclo[2.2.1]heptan-2-one followed by addition of aqueous sodium hydroxide. N-H...O hydrogen bonds link the molecules ...
    • 1,1’-联萘-2,2’-二酚-单-[(-)-孟基]碳酸酯旋光异构体的反相高效液相色谱分离及光学纯度测定 

      阮源萍; 陈安齐; 刘文远; 郑锦丽; 黄培强 (厦门大学, 2000-11)
      采用反相高效液相色谱法分离了 1 ,1’-联萘 - 2 ,2’-二酚 -单 [(- ) -孟基 ]碳酸酯旋光异构体 .考察了这一对旋光化合物的反相高效液相色谱行为 .结果表明 ,C1 8及 C8柱和醇 /水流动相体系适合于这一对旋光异构体的分离 .进一步优化了色谱分离条件 ,并用于它们的光学纯度测定。 R)1,1’inaphthalene2,2’diolmono[()menthyl] carbonate and ...
    • 1,1’-联萘-2,2’-二酚及其孟基碳酸酯衍生物的手性高效液相色谱 

      阮源萍; 敖小平; 陈安齐; 黄培强; 靳立人 (厦门大学, 2002-03)
      用高效液相色谱法考察了 1,1’ 联萘 2 ,2’ 二酚及其单和双氯代孟基碳酸衍生物等三对手性化合物在 (S) 特 亮氨酸基 (S) 1 (α 萘基 )乙胺脲型手性色谱柱上的拆分行为 .讨论了三元流动相中 1,2 二氯乙烷和乙醇含量的变化以及不同极性调节剂对分离的影响 ,探讨了这些手性化合物在脲型手性固定相上的可能拆分机理 .该法已用于 ( ) 孟基氯代碳酸酯化学拆分外消旋 1,1’ 联萘 2 ,2’ 二酚过程相关产物的光学纯度测定. The ...
    • 1,2,3,4,4b,4c,6,7,8,9,9b,9c-Dodecachloro-4b,4c,9b,9c-tetrahydrocyclobuta[1,2-a;3,4-a ‘]diindene-5,10-dione 

      Peng, Y; Xie, SY; Long, LS; Huang, RB; Zheng, LS; 谢素原 (BLACKWELL MUNKSGAARD, 2004-05)
      The title compound, C18Cl12O2, was synthesized by a solvothermal reaction between sodium and carbon tetrachloride; the oxygen may come from air. The molecule has crystallographic C-2 symmetry and contains a four-membered ...
    • 1,2,3,4,4b,4c,6,7,8,9,9b,9c-Dodecachloro-4b,4c,9b,9c-tetrahydrocyclobuta[1,2-a;3,4-a']diindene-5,10-dione 

      Yin Peng; 彭银; Su-Yuan Xie; 谢素原; La-Sheng Long; 龙腊生; Rong-Bin Huang; 黄荣彬; Lan-Sun Zheng; 郑兰荪 (BLACKWELL MUNKSGAARD, 2004-08)
      The title compound, C18Cl12O2, was synthesized by a solvothermal reaction between sodium and carbon tetrachloride; the oxygen may come from air. The mol­ecule has crystallographic C2 symmetry and contains a four-membered ...
    • 1,2,3,5,6,7,8,9-octachlorocyclopenta[def]phenanthren-4-one 

      Yin Peng; 彭银; Su-Yuan Xie; 谢素原; Shun-Liu Deng; 邓顺柳; Rong-Bin Huang; 黄荣彬; Lan-Sun Zheng; 郑兰荪 (BLACKWELL MUNKSGAARD, 2004-05)
      The title compound, C15Cl8O, was separated from the products of a solvothermal reaction of metallic sodium and carbon tetrachloride in air in a pressured autoclave. The molecule is bisected by a crystallographic mirror ...
    • 1,2-Azaborolyl和硼杂苯铑配合物的合成与催化性质及1,2-Azaborolyl钌亚乙烯基配合物的反应性质研究 

      朱鹏飞 (2018-02-26)
      1,2-氮硼杂环戊二烯基(1,2-azaborolyl,Ab)和硼杂苯(boratabenzene,Bb)作为环戊二烯基(Cp)潜在的替代配体,能形成众多的金属有机配合物。然而,目前很少有人研究含这两类硼杂环的铑配合物,仅有零星的几例报道。特别是含这两类硼杂环的半夹心型Rh(III)配合物未见报道。鉴于Cp以及Cp*配位的半夹心型Rh(III)具有丰富的催化性质,本论文研究了1,2-azaborolyl和硼杂苯Rh(III)配合物的合成 ...
    • 1,2-丙二醇选择性氧化合成丙酮醛:Ag/ZrO2催化剂的生物法制备 

      王慧 (2011-02-18)
      丙酮醛(MGX)是一种重要的有机合成中间体,主要用作药物中间体,也广泛用于制备农药、食品添加剂等。丙酮醛通过与甲醛、氨等反应可以制得医药中间体4-甲基咪唑,还可以通过歧化反应制得用途广泛的乳酸。近年来随着咪唑以及呋喃酮等香料需求的增加,丙酮醛的需求量也日益增加,但它的天然存在量很少,而国内丙酮醛的生产起步晚,且规模较小。另外,丙酮醛的传统制备方法中所采用的催化剂多为电解银催化剂,电解银催化剂在反应温度低于500℃时活性不够,产物中有较多 ...
    • 1,25(OH)2D3抑制同种反应性CD4+记忆性T细胞介导的移植排斥反应 

      席艳峰 (2012-12-25)
      目的:供者反应性记忆性T细胞(memoryTcells,Tm)介导的移植排斥反应是目前器官移植领域难以攻克的主要障碍之一。CD4+Tm是Tm家族的主要成员之一,在记忆性移植排斥反应中发挥重要作用。在本研究中,通过体外验证1,25(OH)2D3能否抑制CD4+Tm的免疫活性,结合体内实验研究1,25(OH)2D3与CD4+Tm介导的移植排斥反应之间的关系,而且进一步探讨相关实验结果的发生机制。方法:在同种异体小鼠间进行皮肤移植,移植后4- ...
    • 1,25(OH)2D3联合单克隆抗体延长小鼠加速性排斥模型中心脏移植物生存期的研究 

      闫国良 (2015-05-07)
      目的:供者反应性记忆性T细胞(memoryTcells,Tm)介导加速性排斥反应,是诱导移植物耐受的主要障碍。本研究利用1,25(OH)2D3和封闭性单克隆抗体anti-CD154/anti-LFA-1对Tm介导的加速性排斥反应进行治疗,比较不同用药组合对移植物的保护作用并探索该方案的作用机制。 方法:首先通过同种异体皮肤移植得到预致敏小鼠,过继转移同种反应性记忆性T细胞,构建小鼠同种异体心脏移植模型后再联合1,25(OH)2D3和an ...
    • 1,2:3,4:5,6-Tri-O-isopropylidene-d-mannitol 

      Liu, P.; Wen, T. B.; Cheng, J. K.; 温庭斌 (1999)
    • 1,3,4,6,7,9-Hexabromo-2,3,4,5,6,7,8,9-octahydro-1H-trindene 

      Sheng-Jun Zhou; 周胜军; Su-Yuan Xie; 谢素原; Rong-Bin Huang; 黄荣彬; Lan-Sun Zheng; 郑兰荪 (BLACKWELL PUBLISHING, 2007-09)
      Each of the six Br atoms in the title compound, C15H12Br6, connects to an alpha-C atom; a pair of adjacent Br atoms connecting to the same five-membered ring extends to one side of the molecular framework and the other two ...
    • 1,3-di-2-pyridylthiourea monohydrate 

      Zhong, HP; Long, LS; 龙腊生; Huang, RB; 黄荣彬; Zheng, LS; 郑兰荪; Ng, SW (BLACKWELL MUNKSGAARD, 2003)
      The title compound, C11H10N4S.H2O, displays an intramoleculear N-amido...N-pyridyl hydrogen bond [2.652 (2) Angstrom] that locks the thiourea unit and one pyridyl ring into coplanarity [dihedral angle 2.7 (1)degrees]. The ...